Hi daveclark,
Try clearing the MobiOne metadata as follows:
1) open the task manager and ensure there is not a zombie version of mobione.exe running
– if you find a process running, kill it and then try launching mobione again. If mobione.exe does not start proceed to #2
2) clear the mobione metadata by deleting this directory and then launch mobione
<user-home-dir>\.mobione\.metadata\runtime\plugins, e.g., C:\Users\Octavio\.mobione\runtime\.metadata\plugins
Let us know if this resolves the issue.